ODDS RATIO IN ASSESSING THE RISK OF HEART REMODELING IN PATIENTS WITH CORONARY HEART DISEASE

ZHARILKASINOVA G.ZH, GANIEVA SH.SH.

Key words:

CARDIOVASCULAR DISEASES, CORONARY HEART DISEASE, ARTERIAL HYPERTENSION, RISK FACTORS

Abstract:

Introduction. The risk of cardiovascular complications and death rises in tandem with the frequency of angina attacks. If the frequency exceeds 6 attacks per week, patients face a threefold increase in the risk of developing cardiovascular complications. It is widely acknowledged that targeting myocardial ischemia may constitute an effective approach to mitigating the risk of adverse outcomes. Purpose of the study. To develop a risk stratification program for cardiac remodeling in middle-aged and elderly individuals with cardiovascular diseases.

 

Materials and methods. The study comprised 116 middle-aged and elderly patients diagnosed with cardiovascular diseases, with an average age of 62.4±1.27 years. All participants underwent examination at the Bukhara branch of the Republican Scientific and Practical Center for Emergency Medical Care.

 

Results. In the course of the study, it was established that in patients with ischemic heart disease and arterial hypertension, the level of creatinine in the blood increases by 2.3 times. It was also found that inflammation intensifies when the number of leukocytes in peripheral blood decreases to less than 4.0 or increases above 9.0.

 

Conclusions. In the hierarchy of the frequency of occurrence of risk factors for cardiac remodeling, the primary position is held by elevated blood creatinine (>100 mmol/l) with an odds ratio (OR) of 22.9. Following closely are obesity factors and high R V5-6, deep S V1-2 (on the ECG) with OR of 16.0. The third position is attributed to the factor of stress and/or mental load, showing the OR of 14.0.